Isotretinoin (Accutane) Rx Only
Generic for Accutane · Oral retinoid for severe nodular acne
from $2.49
- Prescription required. Dispensing requires active enrollment in iPLEDGE and meeting all program steps.
- Monthly pregnancy testing and labs as directed by your clinician.
- Insurance accepted: Most major plans (Anthem, Cigna, Aetna, UnitedHealthcare).
- Reviewed by licensed pharmacists.
How ordering Isotretinoin works
- Send us your prescription and ensure you are enrolled/active in iPLEDGE (prescriber and patient). We verify eligibility windows.
- We verify your Rx, confirm required tests (e.g., pregnancy tests, labs), check interactions, and contact you if anything needs attention.
- Choose pickup or delivery at checkout within the iPLEDGE dispense window. Most refills follow monthly monitoring.
Important safety information (summary)
Do not use if
- You are pregnant or may become pregnant—teratogenic. Two forms of contraception (or continuous abstinence) required per iPLEDGE.
- You are breastfeeding.
- You have known allergy to isotretinoin, soy, or product components.
Common side effects
Dry lips/skin/eyes, nosebleeds, sun sensitivity, joint/muscle pain, elevated triglycerides or liver enzymes. Seek care for mood changes, severe headache/vision changes, chest pain, or pancreatitis symptoms.
Program requirements
iPLEDGE monthly confirmations, pregnancy testing for patients who can become pregnant, and lab monitoring as directed. Do not share or donate blood while on therapy and for 1 month after.
This page is informational and not a substitute for medical advice. See full information below.
What is Isotretinoin?
Isotretinoin (formerly brand Accutane) is an oral retinoid used for severe recalcitrant nodular acne unresponsive to other treatments. Dispensed by Serv-U Pharmacy only with a valid prescription and full iPLEDGE compliance.
Uses
- Severe nodular acne unresponsive to conventional therapy
- Other uses only if directed by your clinician per labeling and program rules
Only your clinician can determine if isotretinoin is appropriate for you.
How it’s taken (follow your prescription)
Take exactly as prescribed. Many products should be taken with food to improve absorption; certain micronized formulations may be taken without regard to meals—follow your label.
| Form | Strengths (examples) |
|---|---|
| Capsules | 10 mg, 20 mg, 30 mg, 40 mg |
Do not crush or open capsules. If you miss a dose, take it when remembered unless it’s near the next—do not double up. Pharmacist counseling is available at checkout.
Warnings & interactions
- Pregnancy: Absolute contraindication. Strict iPLEDGE compliance is required.
- Liver & lipids: May increase liver enzymes and triglycerides—lab monitoring as directed.
- Psychiatric: Report mood changes, depression, or suicidal thoughts immediately.
- Ocular/skin: Dryness, vision changes; use lubricating drops and sunscreen.
- Interactions: Avoid vitamin A supplements, tetracyclines (risk of intracranial hypertension), and limit alcohol (triglycerides/liver).
- Blood donation: Do not donate during therapy and for at least 1 month after.
Storage
Store at room temperature away from moisture and light. Keep out of reach of children.
FAQ
Is Accutane still available? The original brand was discontinued; FDA-approved generics (isotretinoin) are available.
Do I need to be in iPLEDGE? Yes—patients, prescribers, and pharmacies must all comply for each monthly fill.
Do I take it with food? Many isotretinoin products should be taken with meals; follow your specific product label.
Do you accept my insurance? We accept most major plans. Enter your details at checkout to see your copay.
Sources & review
- FDA Prescribing Information for Isotretinoin (generic products)
- iPLEDGE REMS program materials
- NIH MedlinePlus: Isotretinoin
Medically reviewed by Judy Doyle, PharmD — Licensed Pharmacist (NPI 1699814004) · Last updated
Price & insurance estimator
Reviewed by our pharmacist
Judy Doyle, PharmD — Licensed Pharmacist (NPI 1699814004).
We’ll guide you through iPLEDGE steps, timing of tests, and safe-use counseling (sun protection, moisturizers, avoiding vitamin A and tetracyclines). If you notice mood changes, severe headaches, or vision issues, contact your prescriber immediately.
How to spot a legitimate online pharmacy
- Requires a valid U.S. prescription for Rx medications.
- Displays state pharmacy license and physical address.
- Has NABP Digital Pharmacy or state board verification.
- Secure checkout; clear privacy practices (HIPAA).
- Offers pharmacist consultation.
Verify licenses with your state board or NABP listings.